Wednesday, April 18, 2012

7. How would you explain the connection between glucose entering the body and energy created by the body to a friend, using your new biochemistry knowledge?

      Glucose enters the body and undergoes many changes in order for the body to create energy. First glucose enters the body and a phosphate attaches to the glucose molecule to create glucose 6-phosphate, this phase actual results in a loss of energy since the phosphate comes from ATP and converts to ADP. Then the glucose 6-phosphate rearranges into fructose 6-phosphate where after another phosphate attaches creating fructose 1, 6-diphosphate and more energy is being used. This molecule then splits into two different molecules: dihydroxyacetone phosphate and glyceraldehyde 3-phosphate. The dihydroxyacetone phosphate rearranges into glyceraldehyde phosphate since they are isomers (same amount of molecules in a different arrangement) the process then continues with 2 glyceraldehyde 3-phosphate molecules which turn into 2 molecules of 1, 3-bisphosphoglycerate which then loses a phosphate molecule to create 2 molecules of 3-Phosphoglycerate, which now creates 2 molecules of ATP (energy) for a net of 0 ATP created. These molecules then rearrange into 2 molecules of 2-Phosphoglycerate then it loses water and becomes phosphoenolpyruvic acid. Then the 2 molecules of phosphoenolpyruvic acid loses a phosphate which results in 2 ATPs created which is more energy created. Phosphoenolpyruvic acid then either transforms into Acetyl CoA, ethanol and carbon dioxide, or lactic acid. If it turns into Acetyl CoA it will then enter the Krebs cycle where a lot of energy is created because the molecules lose phosphate groups which results in ATP which is your primary energy source.

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